Endocrine Abstracts

Introduction: As the incidence of thyroid cancer is increasing, so are the cases of recurrence with RAI refractory metastasis of thyroid differentiated cancer. We present such a caseCase report: A 77-year-old female with a medical history of papillary thyroid carcinoma recurrence 10 years after surgery with successful 3 RAI sessions and normal thyroid cancer markers after treatment until her recurrence a year ago, with TSH unstimulated thyroglobulin of 1...

We present the history of two brothers, 19 and respectively 21 years old who were admitted in our department for reevaluation in the context of renal complications. From their medical history we keep in mind that central DI was diagnosed 15 years ago and desmopresin treatment was indicated. Meanwhile, patients received desmopresin unsteady for very short periods of time (less than 2 years) due to poor adherence and obvious inefficiency of the treatment. They claim medical care...

Introduction: We report a case of adrenal tumor recurrence after bilateral adenomectomy for Cushing’s syndrome.Case report: A 44-year-old female diagnosed in June 2014 with Cushing’s syndrome caused by bilateral adrenocortical tumors, which were identified by an abdominal CT (right tumor-2.6/ 2/1.8 cm, left tumor-3/2/2 cm). At presentation, the patient had typical signs and symptoms of hypercortisolism and complications such as: arterial hypert...

Background: The surgical technique and the extent of thyroidectomy are related to parathyroid injury and hypoparathyroidism.Methods and results: We retrospectively analyzed the files of 552 patients who underwent thyroidectomy in our surgery department between 2015-2017 with the aim to assess the incidence and impact of intraoperative features that may predispose to postoperative hypoparathyroidism (PoSH).Results: 171 (30.97%) pati...

Background: Quality of life (QoL) has become a useful outcome in recent studies among different specialties. In Cushing’s syndrome, elevated cortisol levels result in a decreased QoL, the cause for this impairment being multifactorial. More studies are necessary to find modifiable factors where doctors could intervene and thus improve QoL.Objective: To evaluate QoL in a group of Romanian patients with Cushing’s syndrome. Design: We performed a ...

Introduction: Insulin-like growth factor 1 (IGF-1) is an established serum marker for both diagnosis of growth hormone (GH) deficiency and for monitoring treatment with Somatropin, whether it is recommended for the classic GH-insufficient short stature cases or for other GH-sufficient disorders.Aim: To evaluate whether serum level of IGF-1 at diagnosis has a predictive value for the response to somatropin treatment during the 2 years of treatment in chil...

Introduction: Signs of hyperandrogenism are frequent complaints for young adults and adolescents and a common cause of presentation to endocrinology service. Even if polycystic ovary syndrome is the most frequent etiology, differential diagnosis is mandatory. (1,2)Case report: We present the case of a 26-year-old female patient, obese, smoker, with a personal history of polycystic ovary syndrome and a family history of diabetes mellitus, who presented to...

Background: A large body of evidences have demonstrated that metabolic surgery is associated with significant and durable weight loss as well as a significant improvement of obesity-related comorbidities. The aim of our study was to evaluate the long term impact of gastric sleeve on metabolic parameters in morbidly obese patients.Materials and methods: We evaluated 95 (67 women) severely obese patients (mean age 43.4±10.69 years) before and approxim...

Introduction: Vitamin D is a hormone essential for calcium absorption and bone mineralization, which is positively associated with bone mineral density. The aim of our study was to evaluate the relationship between 25-OH vitamin D values and parameters of bone mineralization (bone mineral density - BMD) and bone quality (trabecular bone score - TBS) in patients from day to day clinical practice.Materials and methods: We evaluated 433 postmenopausal women...

Introduction: Graves’ disease is an autoimmune disease that leads to a generalized overactivity of the entire thyroid gland – hyperthyroidism. Although the link between Graves’ disease and thyroid carcinoma was widely explored, we cannot undermine the relationship between this condition and other common neoplasms.Materials and method: The retrospective analysis was performed using clinical data of 295 adult patients (225 women and 70 men) ...